We are a computational biochemistry group based in the School of Biochemistry at the University of Bristol. Research in the group focuses primarily on computational enzymology: elucidating enzyme mechanisms and catalysis, understanding and predicting β-lactamase mediated antibiotic resistance, and investigating the relationships between protein dynamics, interactions and conformational change. We work closely with experimental collaborators in Bristol, the UK and around the world.
We use a range of biomolecular simulation and modelling methods, including combined quantum mechanical / molecular mechanical (QM/MM) modelling and (enhanced sampling) molecular dynamics, and also (co-)develop and apply new simulation methods.
For further info, take a look at our research page or browse through our publications!
Van der Kamp Group 